Sadow Group work is focused upon the development of new catalytic reactions and new catalysts for application in green chemistry, stereoselective synthesis, and the conversion of abundant raw materials into commodity and specialty chemicals. This work impacts energy sciences and chemical production. Our approach involves the design and study of main group, early transition-metal, and rare earth organometallic compounds as catalysts for transformations of polar, oxygen- or nitrogen-containing substrates. We study structure and reactivity through a combination of spectroscopy and kinetics to better understand catalytic reactions, the chemical properties that make a good catalysts, and to design new transformations.